Space flight simulator 201012/7/2023 ![]() We introduced the reverse experimental approach by fixing salt intake of men participating in space flight simulations at 12 g, 9 g, and 6 g/day for months and tested for the predicted constancy in urinary excretion and total-body Na + content. The steady-state concept of Na + homeostasis, based on short-term investigations of responses to high salt intake, maintains that dietary Na + is rapidly eliminated into urine, thereby achieving constant total-body Na + and water content.
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